I thought the beginning was a little bit ridiculous with the "where were you when JFK was assasinated" line. I would estimate that 98% of the viewers of V weren't even a twinkle in their daddy's eye when JFK was assasinated. The geezers are watching Matlock reruns, not V.
And I agree with the comments on pacing. The entire episode was incredibly rushed. It felt like an anti-Heroes; while Heroes drags ridiculous storylines out for months on end, V took a compelling storyline and crammed a good three or four episodes worth into a one hour pilot.
No mystery whatsoever about whether the Visitors are actually benevolent is a negative.
Every time Hollywood has a doomsday situation in need of a religious character, why is it always a Catholic priest?
Also, do the writers really think so little of the human race to assume the vast majority of us can be bought off with medical cures and hot alien chicks?
All those criticisms said, I liked it enough to give it another go next week.